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The popularization of yoga in the West by yoga schools influenced by the Yoga Sutras Of Patanjali (2nd century BC), have almost led to the origins of yoga bein

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

g linked with Patanjali in the Western mind. In fact, the earliest illustration we have of yoga is from the Mohenjo-daro seals. Mohenjo-Daro is the remains of

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

an ancient city located in Pakistan, part of the Indus Valley civilization which existed along the Indus river and Ghaggar-Hakra river in north-west India and

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

what is now Pakistan. Mohenjo-Daro's parent city was Harrapa in India.

These civilizations have been dated from 3300 BC to 1300 BC. At one stage they were tho

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ught to have suddenly ended due to an Aryan invasion, though archaeologists now believe it was more likely due to climate change. Ultimately though, nothing is

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

certain in the world of archaeology, at least until the next find, or developments in science.

The Mohenjo-daro seals show a figure standing on its head, and

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

another sitting cross legged.

However, some see yoga's origins as being from the Vedic shastras, or vedic religious texts, which are the foundation of Indian

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Hinduism. The Vedic texts were created from 500 BC, and the Rigveda is believed to have been completed by 1500 BC. The Rigveda is one of several principle earl

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

y vedic texts. The Rigveda, Samaveda, and Yajurveda were used by the Brahmins, a caste that were usually priests, or allowed to be priests, in the days when th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e caste system originated.

A lot of these texts were concerned with sacrificial rituals. There are sacrificial prayers, incantations, and elements related to

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

magic, to name a few aspects of the subject matter. These are now viewed symbolically, or philosophically, although they were presumably intended more literall

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

y at the time. But the word "yoga" was discussed in the RigVeda. In it, there is mention of 'yoking' our mind and insight to the 'Sun Of Truth' (David Frawley,

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

a Vedic scholar).

Yoga is also discussed in the Bhagavad Gita, where Krishna describes 4 types of yoga:

* selfless action - in following one's soul path, on

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

e's dharma, first and foremost, and without thinking of the outcome, the end result, or being motivated by self gain (Karma Yoga)

* self transcending knowledg

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

(Jnana yoga)

* psycho-physical meditation (Raja yoga)

* devotion - loving service to the Divine Essence (Bhakti yoga) (Source - Wikipedia)

The Bhagavad Git

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

a is believed to have been written between the 5th and 2nd century BC. In the Gita, the goal of yoga is the realization of Brahman, or the Divine Essence. Whil

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

st the paths to achieve this for individuals may be different, the essence of coming to an unequivocable knowing of the Oneness of the Divine, and oneself with

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

in this fundamental reality, is the same.

"The Gita addresses the discord between the senses and the intuition of cosmic order. It speaks of the Yoga of equan

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

imity, a detached outlook. The term Yoga covers a wide range of meanings, but in the context of the Bhagavad Gita, describes a unified outlook, serenity of min

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

d, skill in action, and the ability to stay attuned to the glory of the Self (Atman), which is of the same essence as the basis of Being (Brahman)." (Wikipedia

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Every little girl dreams of having a fairytale wedding and looking the glowing, absolutely radiant bride on her special day. Women always say that it's wonderful to be marrying someone who loves them just the way they are; but on the day the knot is tied, nothing less than perfection is expected. Now there are wedding planners to help ensure the event goes smoothly, caterers to serve great food and family to take care of the guests. That just leaves the bride's looks.

It is an intricate situation; Most states or local administrations do not have enough funds to examine and monitor all those who need medical treatment, especially those suffering from chronic diseases like diabetes and asthma. So what if a pharmaceutical company puts up the funds to have qualified nurses visit doctors' offices to review the charts of the patients and to assess their progress? Such nurses sometimes also provide much needed professional development training for the office staff as well.

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