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The original meaning of the word 'yoga' was not limited to the asanas or postures that are synonymous with Yoga in the West. The word yoga itself means union, and yoga was taken to mean

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

any path which led the spiritual seeker to union with his highest Self, or union of the individual soul with the Universal Soul. In this sense, Yoga can trace its origins far back to the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

dawn of spirituality, to the time of the ancient Vedic seers, and possibly even before.

Over time, different yogic paths evolved reflecting the different types of human temperament. In

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

the Bhagavad Gita, India's most famous scriptural work, three main types of yoga were described:

Bhakti Yoga was for people whose natural spiritual tendency was to approach the

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Highest through love and worship. In India, Lord Krishna was a central focus for those following bhakti yoga, and the popularity of this path grew in the 15th and 16th centuries through

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

the life and example of such great figures as Sri Chaitanya, Mirabai, and Kabir. This kind of yoga is probably most familiar to us in the West as the approach to God used in Christianit

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

Jnana Yoga: the path of knowledge, through studying books and scriptures, but more importantly through self-introspection. One famous 20th century jnana yogi, Raman

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

a Maharshi, would commonly ask those seeking his guidance to contemplate on one simple question 'Who am I?'. The Buddha was also a jnana yogi

Karma Yoga is for those who

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

wish to make progress through staying in the world; it tells us to act selflessly, without attachment to the results of our actions. It means seeing and serving God in humanity; a famil

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

iar example would be the work of Mother Teresa. The meaning we in the West give to Yoga today stems from the Yoga Sutras, which were written around 200AD by Patanjali and ar

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e generally considered to be the classic description of yoga. This text is looked upon as one of the six darshanas, or branches of traditional Indian philosophy. In this text, Patanjali

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

describes an integral system of living called Raja Yoga, which included as one of its components a series of physical postures called asanas. In the West, the term yoga is gene

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rally taken to mean the practice of these asanas, which in addition to giving a sense of wellbeing, were also meant to prepare the body to be able to sit for long hours in meditation and

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

contemplation.

A very influential text in the spread of these asanas was the Hatha-Yoga-Pradipika, written in the 14th century by Svatmarama. Hatha Yoga is a broad term usuall

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

y used to describe the physical postures and breathing (pranayama). In the 16th and 17th century, this kind of yoga grew in popularity and was strongly influenced by Tantric principles.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

The spread of yoga in the West can be partly attributed to such spiritual figures as Swami Vivekananda and Paramhansa Yogananda, who first awakened the interest of Western seekers in E

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

astern philosophy in the late 19th and early 20th centuries with their expositions of jnana, bhakti and karma yoga. the promotion of Hatha Yoga in the 1920's by T. Krishnamacharya and t

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

he work of his students B.K.S Iyengar, T.K.V Desikachar and Pattabhi Jois have had a profound influence in shaping the yoga performed in today's yoga studios. The physical postures of H

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

atha Yoga found popularity with people in the West who were seeking physical and emotional balance rather than full-fledged enlightenment, and many styles evolved as individual teachers

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

emphasised different aspects of the practice. For example, Iyengar Yoga emphasises precise alignment in the posture work, whereas Ashtanga Yoga concentrates more on strength and agility

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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