Article Dump - Health and Fitness

Are you a contact lens wearer who does not like to have to remove your contacts, insert your contacts, clean them, store them

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

, etc.? I got good news for you, there is a new type of contact lens, extended wear contacts, that you can wear for many days

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

without having to deal with the problems above. Are they safe for you though?

Before even wondering if they were safe for m

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e I would consider if they were more expensive than regular contact lenses. I was surprised when I found out that they are no

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

t that much more expensive. They are cheaper than daily disposable contacts and are not that much more expensive than weekly

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

or monthly disposable contacts. In fact, in the long run extended contacts may even save you money because you will not have

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

to buy contact solution.

Now that we know that they are not that much more expensive and you may actually save money in the

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

long run, lets look at the safety of them.

Contact lenses that are worn daily are required to be taken out at night, but why

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

? The reason you must take the lens out is because the lens blocks the flow of oxygen to your cornea so your eyes need a brea

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

k from the lens. This is a problem that contact lens manufacturers have been trying to fix so that contact wearers do not hav

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e to have the problem of dealing with removing and inserting their contacts daily.

Thanks to modern technology contact lense

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s are now able to allow through about six times as much oxygen and the original contact lenses. Extended contact lenses are n

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ow made of extra-permeable silicone hydrogel materials which allows the contacts to let enough oxygen in that it is no longer

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

a problem for you to wear the contacts for several days in a row.

What does that mean though? It means that these new exten

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ded contact lenses are safe to wear as long as you follow your doctor's instructions. The only problem is because you do not

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

clean them every day particles of dust can build up on them, so follow the following rules:

1. Avoid dusty rooms and cigaret

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

te smoke.

2. Keep water out of your eyes when you shower and wear goggles when swimming.

3. Wear the contact lenses only fo

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

r the time they are meant to be worn. This means only wear extended contact lenses meant for a week only for one week and tho

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

se meant for 30 days only for 30 days.

If you do not like to remove, clean, and insert your contact lenses every day and nig

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ht then you should consider extended wear contact lenses which are safe to wear provided you listen to what your doctor says.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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