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    I am very concerned about our young, and maybe not so young, women today, who seem ob
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    sessed with loosing enormous amounts of weight.

    The problem stems from the images of
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    all the grotesquely thin celebrities who feature in magazines and on web sites. You
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    ng girls begin to think the wafer-thin image is the norm, and begin dieting to get do
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    wn to the desired, size Zero.

    Young girls, and as I wrote earlier, maybe not so youn
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    g women, are damaging their bodies with this extreme dieting, and I want to alert you
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    all to the risks.

    When you have lost all your fat, you begin to loose muscle. You
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    become weaker and are always exhausted.

    As your body weakens, so does your brain! Y
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    ou will suffer from concentration problems, sleep disturbances and you may develop a
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    chemical imbalance in the brain, which could lead to mental problems. The brain, lik
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    e the rest of the body, needs calories to survive.

    The immune system will become com
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    promised, leading to infections. Your fertility may also be affected, and if you con
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    tinue dieting, you could forever loose your chance to conceive, because you may enter
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    an early menopause, from which, even if you begin eating normally, you will not reco
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ver.

    Eventually, extreme dieters loose the desire to eat and then they really are at
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    risk. But what's to be done?

    Magazines and websites should not feature these ultra
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    -thin celebrities. They should, instead, feature the female celebs who have not pand
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ered to the image of Size Zero, and men should tell their wives and girlfriends that
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    they don't find thin celebs sexy. I hope this image doesn't continue, because all of
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    the size zero celebrities, and the girls who copy them, are quite literally... DYING


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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