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Since the causes and mode of progress of Alzheimer’s disease is still a riddle to experts in this field, some preventive measures at least may put a check on

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

this distressing disorder. In course of random search, it was observed that people with a family history of Alzheimer’s are prone to become victims while stud

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

es have shown that the disease may set in as a person begins to age. So, if your family tree has several black spots indicating Alzheimer’s, you better be car

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ful. Even without any family history, an aging individual should also take the following measures for prevention of Alzheimer’s disease.

Lifestyle changes

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

for the prevention of Alzheimer’s disease

Though difficult at the outset, lifestyle changes, change of outlook and active mental and physical routine are

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

supposed to render help in prevention of Alzheimer’s disease. To begin with, let us see how mental stimulation may assist in the prevention of Alzheimer’s dis

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ase.

Health studies conducted on nuns revealed that those who participated regularly in intellectual pursuits were less likely to contact Alzheimer’s. Furthe

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

r studies also proved that a mere brainwave might not put a stringent check on Alzheimer’s altogether, but it certainly delayed the onset and the progression

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

f the symptoms that are no less distressing. So, for prevention of Alzheimer’s disease one could just about read adventure stories, travel literature, sci-fi

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

tories or do Crossword puzzles, play chess or scrabble.

Physical activity

Recent studies have shown that apart from mental stimulation, certain forms

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

of physical activity may come of assistance for the prevention of Alzheimer’s disease. Since the actual causes are unknown, it is believed that physical activ

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ty promotes increased blood flow, heart and lung capacity, etc and the combined effect should prevent Alzheimer’s disease. However, physical activity need not

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

necessarily be rigorous. Regular daily walk or swim, if possible or a game of golf or better still, any outdoor activity with small children may delay the ons

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t of the disease.

Social Interaction

As people age, they tend to avoid social activity, preferring a solitary existence. However, studies have shown

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

that aversion to social interaction prevents release of certain hormones necessary to build up immunity in human being. So, maintaining a social network, visi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ing friends and relations, attending parties, etc may help in the prevention of Alzheimer’s disease.

Diet

Though no definite diet plan has yet been i

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

troduced for patients suffering fro Alzheimer’s, it is generally believed that diet recommended for cardiovascular diseases is also good for Alzheimer’s. Besi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

es, experts studying in preventive medicine have indicated that antioxidants like vitamin C and E and fish oil play a fairly important role in the prevention

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

f Alzheimer’s disease. In any event, such diet will do more good than harm to any individual, especially when he or she is aging.

Please note that this artic

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e is for educational purposes only, consult your family doctor or a medical expert before ever trying any remedy or treatment for a disease such as alzheimers

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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