Article Dump - Health and Fitness

Have you ever thought to yourself as you are sitting in your dentist's chair, "I really hate Dental X-Rays" and wondered if they are really necessary and why you need them? Your mind may continue to have a conversation like this for instance;

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

"Doesn't he/she know I am broke and can not afford these?"
"Doesn't my Dentist know they make me gag?"
"Doesn't he/she know I am in a hurry to get back to work?"
"I don't have any pain today, so obviously I don't have anything

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

wrong."

"Is my Dentist trying to run my bill up?"

X-Rays are your Dentist's Eyes. The song, "X-Ray Eyes" should be played in office's as a subliminal message to patients. Dentistry today is one of the only professions that is working harder

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

on putting themselves out of business. Dentistry is targeted to PREVENTION. Early detection of a problem is why your Dentist wants you to get X-Rays. If you handicap your dentist by not allowing him/her to have the use of X-Rays, you may actually be sabatogin

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

the "very reasons" you want to deny them. Confusing?

Here are some straight forward facts:

Your Dentist knows you live on a budget, but again we want to stress, early detection can mean early treatment.
If you wait until something hurts th

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

en you have to feel or experience the pain. OUCH!

If you wait until something is visible to the naked eye, or your Dentist's eye (even if he/she is wearing those ridiculous looking spectacle eye glasses that are called loops) you are more likely to ha

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ve a much bigger problem!Let's just say for example that you did not want the X-Rays because they cost $50.00.

If you would have had the X-Rays taken, and a small cavity (carious lesion) was found between two teeth you may have been look

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ng at a 30-45 minute appointment that might have cost you around $150.00. Your total bill for everything is roughly $200.00 with less than 2 hours missed work time.Now, let's go back to the patient who refused the X-Rays because of one of the abo

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ve mentioned reasons.

Murphy's Law usually plays a little role in making you take care of dental treatment you really don't want to do. You are on vacation, it's the weekend, it's the middle of the night, etc.. All of a sudden, WOW!! A tooth ache,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

or something is hard in your cheese sandwich, or it kills to swallow hot/cold beverages to the point you are running for the biggest bottle of ibuprofen you can find.Your Cavity that was too small to see with the naked eye has grown. Now you hav

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

to go back to your dentist. If you can survive the rest of the weekend, trip, night, etc. and get an appointment with him/her (which means missing more work) you are now in for another office visit exam charge.

Let's round the numbers off to help make this

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

example easier to follow.

2nd office visit to Dentist --- $50.00
He/she is going to need an X-Ray to diagnose how extensive the decay is --- $50.00.

Lets say your tooth broke off in your sandwich because it was decayed and became wea

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

k. You are now going to hear options that sound like he/she is talking in code to his/her assistant. You don't know what a MODL-4 surface amalgam restoration with a pin retention vs. a porcelain fused to high noble crown with a post and core buildup is, but y

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ou are pretty sure it is NOT CHEAP. Then you swear he/she mumbles something really fast that sounded like he/she said there is always a chance the nerve of the tooth is dead and you will someday need a root canal. WHAT? Those two words in a dental chair have

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ade many comedians rich, and you really could have lived the rest of your life without experiencing it first hand?

Ok, let's see what the damage is for grins (pardon the pun):

2nd visit to Dentist --- $50.00
X-Ray to evaluate extent of probl

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

em --- $50.00

Crown(cap) to repair decayed/broken tooth --- $1000.00

Total hours in the Dental Chair with a minimum of 2 appointments at roughly 1 1/2 hours apiece plus commute to and from work is --- over 3 hours!

Total cost --- $1100

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

.00!*Added Bonus, you get to go back to work twice with a numb face!

Now let's pretend you were the "unlucky" one who had to have a root canal.

Add another "thousand big bucks" to the grand total
Add "at least" one more 2 hour app

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

intment

More X-Rays!

*Added Bonus, something to complain about at parties with all of your friends!

When we said dentists are trying to put themselves out of business, this is one of our examples. They want the X-Rays so they can

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

find the problem when it first is detectable. They are not trying to torture you, make you gag, run up your bill, etc...They need to be able to see things that are too small to be seen or felt by you the patient. They want to limit the time you a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

re missing work, and they amazingly are trying to save you money in the long run. I know this type of reasoning goes against everything you have thought about your dentist, but that is the real truth to why your dentist wants you to have regular dental X-Rays

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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