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    Protecting our gum tissue is not only critical to the appearance of our smile and keeping our natural teeth, it may also be imperative to our overall health. Studies keep
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    popping up indicating the contribution of gum disease to other diseases of the body such as heart disease. Researchers have discovered that those with periodontal diseas
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    e are not quite twice as likely to suffer from coronary heart disease.

    How can you improve your gum health? There are generally two aspects that contribute to the healt
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    of your gums. They are professional care and home care. Both of these are important. One without the other will not be very effective, unless you can afford weekly prof
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    essional cleanings. Therefore home care is at least equally, if not more, important. Neglecting professional care will not work either. You need both to optimize the heal
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    h of your gum tissue, also called gingiva.

    As far as professional care goes, you might consider utilizing the services of a periodontist over that of a general dentist.
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    The periodontist has specialized training and experience with gum tissue health and disease. In addition, that is the focus of his practice. Just like there are speciali
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    ts in medicine, there are in dentistry as well.

    Practically speaking, my own experience is that the care provided in the periodontist's office, as far as gum health is c
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    oncerned, was far superior. This includes the quality of the professional cleaning service. I found the periodontist's office to be able to provide me with many more det
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ils about the health of my gums including additional tips on how to care for them. This is information that I did not receive at the dentist's office. In fact, the denti
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    st did not refer me to the periodontist, I did that for myself. I am glad that I did.

    The frequency of professional cleanings should be every two or three months when it
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    comes to your gum health. The six month cleaning schedule that everyone is used too is adequate for caring for the teeth but not for the health of our gums. Home care is
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    the second aspect of caring for our gums and it is very important. Without it, most people won't have a chance to keep their gums healthy.

    Brushing and flossing are seld
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    om enough to provide adequate home care. If they were, gum disease would probably not be labeled 'the silent epidemic'. The use of a Perio-Aid and an oral irrigator with
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ydromagnetics are reasonable additions to one's daily routine. There may be other tools that can be helpful as well.

    In short if you have or think you might have gum di
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    sease, visit a periodontist. Learn about performing excellent home care for your gums. More frequent professional cleanings are a plus. With adequate professional and hom
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    care, you stand a good chance of successfully fighting off gum disease or preventing it in the first place.

    Lost gum tissue does not normally grow back. Your periodonti
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    st may be able to perform procedures that help. Restoration is seldom one hundred percent. It is best to prevent problems or to stop a current problem from becoming wors
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    . In the future, medical technology may provide us with more options.

    This article is for information purposes only. It is not meant to provide advice, diagnosis or sug
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    gest treatment. If you have or think you might have gum disease, gingivitis or any other health related problems, visit you dentist or doctor for diagnosis and treatment


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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