Article Dump - Health and Fitness

HEPA is the abbreviation for "High Efficiency Particulate Arrestor {Air filter}." HEPA is not a brand of air cleaner. It is a type of air filter that is used in air cleaning and purification equipment including air cleaners, air purifiers and in high quality vacuum cleaners. Most HEPA air cleaners will filter particles in the airborne environment d

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

own to 0.3 microns in size, at an efficiency rating of 99.97%. They will filter and remove some of the smallest microns of allergens such as dust, smoke, pollen, animal dander, Dust Mite allergen etc. When companies remove asbestos in buildings, and clean up pharmaceutical and other potentially toxic spills, the HEPA filtered air cleaners and vacuu

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

cleaning equipment are the required tools for the job. These air cleaners work by filtering the particulate (allergens) in the air through a HEPA filter, which traps the particles, allowing only the clean air to return back into the indoor environment.

The more times the air is exchanged through the HEPA air cleaner in the room or open area, the

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

etter the air quality. The higher the air exchange rate per hour, the cleaner the air will be in that room. HEPA air cleaners will most efficiently service one room or open area at a time.

NOTE: If you operate a HEPA air cleaner in your bedroom, it will not be able to clean the air in your living room or in other areas of your home. All HEPA Air C

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

eaners can only clean the air in the room or open area they are operating in! They cannot pull the air through walls or doorways. If you put a HEPA air cleaner in the hallway between three bedrooms, you will mostly clean the hallway, not the bedrooms. Most people will place a HEPA air cleaner in all needed bedrooms or home office areas and one in t

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

he family room area where the family hangs out to watch TV together.

The better brands of HEPA air cleaners such as Austin Air and EZ Air will provide up to 15 air exchanges per hour in an average size bedroom and up to 8 air exchanges per hour in a 1000 square foot open room or area. The average {lower quality} department store HEPA air cleaners

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ill only provide approximately 2 to 4 air exchanges per hour in an average size bedroom. In a larger size room or space, these lower quality brands of air cleaners will not provide a high enough air exchange rate to make a noticeable difference in your indoor air quality.

Some high quality HEPA air cleaners also have the added feature of a medical

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

grade ultra-violet light system or EGF system. These air cleaners are often called HEPA air purifiers because they include ultraviolet light systems or Enhanced Germicidal Filtration {EGF} systems that will also quickly kill viruses, bacteria and fungi {mold spores} when the contaminated air enters into the air cleaner and air filter protecting you

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

indoor air environment from biological and virus contamination as well as dust, Dust Mite allergen, pollen, odors and out-gassing chemicals.

The best HEPA Air Purifiers to look for are the TRACS and the Bio-Net. These high quality units also contain pounds of activated carbon and Zeolite blends to quickly absorb and remove out-gassing chemicals f

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

rom your home or office indoor environment. The lower quality brands of HEPA air cleaners and HEPA air purifiers on the market, contain pre- filters that have been sprayed with carbon dust which is extremely short lived and more of a sales gimmick than a viable way of removing odors and out-gassing chemicals. Some of these low quality air cleaners

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

re called HEPA air purifiers. BE VERY CAREFUL WHEN CHOOSING A HEPA AIR CLEANER or HEPA Air Purifier! DO YOUR OWN RESEARCH AND ASK LOTS OF QUESTIONS TO THE PEOPLE THAT KNOW!

Ozone-Ionizer Air Purifiers are often confused with HEPA filtered Air Cleaners and Air Purifiers. The fact is that they operate quite differently. Ozone-Ionizer Air Purifiers d

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

not clean the air by filtration as HEPA air cleaners do. There are two types of Ozone-Ionizer air purifiers. First, ozone/ionizer air purifiers use two steps to clean the air. The ozone purifies the air by oxidation. Ozone is naturally occurring gas. It is created by nature when lightning cuts through the oxygen molecule in the air. It splits the

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

2 molecule into O3, which is ozone. The fresh clean smell after a thunderstorm is the ozone that has just been created. Ozone penetrates into the cellular structure of odor, bacteria and fungus molecules, rupturing the cell wall of the contaminant. After this process is complete, the contaminants and odors are greatly reduced.

The second step in t

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

his system is the ionization. There are two types of ionization. The first is needlepoint ionization where the particulate in the air directly in front of the unit is charged with negative ions. These ionic charges attach to airborne particles such as smoke, dust, pollen, animal dander, etc., forcing the particles to quickly drop out of the air in

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

he breathing environment, down to the ground. These needlepoint ionizers usually cover a five to seven foot area in front area of the ionizer. The second type of ionizer is called radio ionization. Radio ionization is a newer technology that uses similar principles as needlepoint ionization except that the radio ionizer uses a specialized and safe

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

adio wave that ionizes the air for aprox 50 feet right through the walls in all directions. With radio ionization, you can actually drop particles {allergens} out of the air in surrounding rooms. One unit can often cover an entire home. These air purifiers work especially well on removing cigar and cigarette smoke and their odors and that's whom we

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

sell them to SMOKERS!

NOTE: When operating any air purifier that produces ozone, be careful to adjust the ozone level as per factory instructions. Ozone can be an irritant to your mucus membranes if turned up to high. This is especially true for people with asthma and lung problems.

REMEMBER, HEPA Air Cleaners are best for removing airborne aller

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

gens, out-gassing chemicals and odors from your indoor air environment. HEPA Air Purifiers with Ultraviolet Light Systems add the ability to also kill and control mold spores bacteria and viruses in your indoor air environment. Ozone-Ionizer Air Purifiers are best for quickly removing cigarette and cigar smoke and odors from your indoor environment

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

For families with smokers and allergy problems sometimes the most effective solution will require the use of an Ozone-Ionizer Air Purifier in the smoking area of your home and HEPA Air Cleaner{s} or HEPA Air Purifier{s} in the bedrooms for the people in the home with allergy problems.

It is very important to utilize HEPA Air Cleaners or HEPA Air

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

urifiers to capture and remove allergens, particulates and if needed to also kill viruses and biological contaminates in your sleeping areas. Our customers report that they sleep more soundly and wake up feeling more refreshed with less allergy and asthma symptoms with a high quality HEPA Air Cleaner or HEPA Air Purifier operating in their bedrooms

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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